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Hepatotoxicity Induced by Isoniazid-Lipopolysaccharide through Endoplasmic Reticulum Stress, Autophagy, and Apoptosis Pathways in Zebrafish

Isoniazid (INH) is a first-line antituberculosis drug. The incidence of adverse reactions accompanied by inflammation in the liver during drug administration to tuberculosis patients is high and severely affects clinical treatment. To better understand the mechanism of hepatotoxicity induced by INH...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Zhang, Yun, Cen, Juan, Jia, Zhili, Hsiao, Chung-Der, Xia, Qing, Wang, Xue, Chen, Xiqiang, Wang, Rongchun, Jiang, Zhenzhou, Zhang, Luyong, Liu, Kechun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496066/
https://ncbi.nlm.nih.gov/pubmed/30858204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01639-18
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