Deleterious Germline Mutations Are a Risk Factor for Neoplastic Progression Among High-Risk Individuals Undergoing Pancreatic Surveillance

PURPOSE: To compare the risk of neoplastic progression by germline mutation status versus family history without a known germline mutation (familial risk) among individuals with an increased risk for pancreatic cancer who are undergoing surveillance. METHODS: Of 464 high-risk individuals in the Canc...

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Bibliografiska uppgifter
I publikationen:J Clin Oncol
Huvudupphovsmän: Abe, Toshiya, Blackford, Amanda L., Tamura, Koji, Ford, Madeline, McCormick, Patrick, Chuidian, Miguel, Almario, Jose Alejandro, Borges, Michael, Lennon, Anne Marie, Shin, Eun Ji, Klein, Alison P., Hruban, Ralph H., Canto, Marcia I., Goggins, Michael
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Clinical Oncology 2019
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ORIGINAL REPORTS
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494358/
https://ncbi.nlm.nih.gov/pubmed/30883245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.18.01512
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