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Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma

PURPOSE: Deleterious germline mutations contribute to pancreatic cancer susceptibility and are well documented in families in which multiple members have had pancreatic cancer. METHODS: To define the prevalence of these germline mutations in patients with apparently sporadic pancreatic cancer, we se...

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Pubblicato in:J Clin Oncol
Autori principali: Shindo, Koji, Yu, Jun, Suenaga, Masaya, Fesharakizadeh, Shahriar, Cho, Christy, Macgregor-Das, Anne, Siddiqui, Abdulrehman, Witmer, P. Dane, Tamura, Koji, Song, Tae Jun, Navarro Almario, Jose Alejandro, Brant, Aaron, Borges, Michael, Ford, Madeline, Barkley, Thomas, He, Jin, Weiss, Matthew J., Wolfgang, Christopher L., Roberts, Nicholas J., Hruban, Ralph H., Klein, Alison P., Goggins, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648172/
https://ncbi.nlm.nih.gov/pubmed/28767289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2017.72.3502
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