Deleterious Germline Mutations Are a Risk Factor for Neoplastic Progression Among High-Risk Individuals Undergoing Pancreatic Surveillance

PURPOSE: To compare the risk of neoplastic progression by germline mutation status versus family history without a known germline mutation (familial risk) among individuals with an increased risk for pancreatic cancer who are undergoing surveillance. METHODS: Of 464 high-risk individuals in the Canc...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Abe, Toshiya, Blackford, Amanda L., Tamura, Koji, Ford, Madeline, McCormick, Patrick, Chuidian, Miguel, Almario, Jose Alejandro, Borges, Michael, Lennon, Anne Marie, Shin, Eun Ji, Klein, Alison P., Hruban, Ralph H., Canto, Marcia I., Goggins, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2019
Assuntos:
ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494358/
https://ncbi.nlm.nih.gov/pubmed/30883245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.18.01512
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