Genome-Wide Somatic Copy Number Alterations and Mutations in High-Grade Pancreatic Intraepithelial Neoplasia

To obtain a better understanding of the genetic alterations of high-grade pancreatic intraepithelial neoplasia (HG-PanIN), we performed whole-genome copy number analysis by using single nucleotide polymorphism microarrays and targeted next-generation sequencing of 11 microdissected HG-PanIN and two...

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Veröffentlicht in:Am J Pathol
Hauptverfasser: Hata, Tatsuo, Suenaga, Masaya, Marchionni, Luigi, Macgregor-Das, Anne, Yu, Jun, Shindo, Koji, Tamura, Koji, Hruban, Ralph H., Goggins, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6024190/
https://ncbi.nlm.nih.gov/pubmed/29684357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.03.012
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