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Chiral Bifunctional Phosphine Ligand Enabling Gold-Catalyzed Asymmetric Isomerization of Alkyne to Allene and Asymmetric Synthesis of 2,5-Dihydrofuran

The asymmetric isomerization of alkyne to allene is the most efficient and the completely atom-economic approach to this class of versatile axial chiral structure. However, the state-of-the-art is limited to tert- butyl alk-3-ynoate substrates that possess requisite acidic propargylic C–H bonds. Rep...

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Vydáno v:J Am Chem Soc
Hlavní autoři: Cheng, Xinpeng, Wang, Zhixun, Quintanilla, Carlos D., Zhang, Liming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492927/
https://ncbi.nlm.nih.gov/pubmed/30789268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b12833
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