A carregar...

Direct observation of prion protein oligomer formation reveals an aggregation mechanism with multiple conformationally distinct species

The aggregation of the prion protein (PrP) plays a key role in the development of prion diseases. In the past decade, a similar process has been associated with other proteins, such as Aβ, tau, and α-synuclein, which participate in other neurodegenerative diseases. It is increasingly recognized that...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Sang, Jason C., Lee, Ji-Eun, Dear, Alexander J., De, Suman, Meisl, Georg, Thackray, Alana M., Bujdoso, Raymond, Knowles, Tuomas P. J., Klenerman, David
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492631/
https://ncbi.nlm.nih.gov/pubmed/31123569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc05627g
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!