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Direct Observation of Murine Prion Protein Replication in Vitro

[Image: see text] Prions are believed to propagate when an assembly of prion protein (PrP) enters a cell and replicates to produce two or more fibrils, leading to an exponential increase in PrP aggregate number with time. However, the molecular basis of this process has not yet been established in d...

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Bibliografiska uppgifter
I publikationen:J Am Chem Soc
Huvudupphovsmän: Sang, Jason C., Meisl, Georg, Thackray, Alana M., Hong, Liu, Ponjavic, Aleks, Knowles, Tuomas P. J., Bujdoso, Raymond, Klenerman, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2018
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225343/
https://ncbi.nlm.nih.gov/pubmed/30351023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b08311
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