Anle138b modulates α‐synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy

BACKGROUND: MSA is a fatal neurodegenerative disease characterized by autonomic failure and severe motor impairment. Its main pathological hallmark is the accumulation of α‐synuclein in oligodendrocytes, leading to glial and neuronal dysfunction and neurodegeneration. These features are recapitulate...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mov Disord
Main Authors: Heras‐Garvin, Antonio, Weckbecker, Daniel, Ryazanov, Sergey, Leonov, Andrei, Griesinger, Christian, Giese, Armin, Wenning, Gregor K., Stefanova, Nadia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6492169/
https://ncbi.nlm.nih.gov/pubmed/30452793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.27562
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados