Docosahexaenoic Acid Increases the Potency of Soluble Epoxide Hydrolase Inhibitor in Alleviating Streptozotocin-Induced Alzheimer’s Disease-Like Complications of Diabetes

Diabetes is a risk factor for Alzheimer’s disease and it is associated with significant memory loss. In the present study, we hypothesized that the soluble epoxide hydrolase (sEH) inhibitor N-[1-(1-oxopropyl)-4-piperidinyl]-N’-[4-(trifluoromethoxy)phenyl)-urea (also known as TPPU) could alleviate di...

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Vydáno v:Front Pharmacol
Hlavní autoři: Pardeshi, Rohit, Bolshette, Nityanand, Gadhave, Kundlik, Arfeen, Mohammad, Ahmed, Sahabuddin, Jamwal, Rohitash, Hammock, Bruce D., Lahkar, Mangala, Goswami, Sumanta Kumar
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491817/
https://ncbi.nlm.nih.gov/pubmed/31068802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00288
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