The ubiquitin proteasomal system: a potential target for the management of Alzheimer's disease

The cellular quality control system degrades abnormal or misfolded proteins and consists of three different mechanisms: the ubiquitin proteasomal system (UPS), autophagy and molecular chaperones. Any disturbance in this system causes proteins to accumulate, resulting in neurodegenerative diseases su...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Gadhave, Kundlik, Bolshette, Nityanand, Ahire, Ashutosh, Pardeshi, Rohit, Thakur, Krishan, Trandafir, Cristiana, Istrate, Alexandru, Ahmed, Sahabuddin, Lahkar, Mangala, Muresanu, Dafin F., Balea, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929298/
https://ncbi.nlm.nih.gov/pubmed/27028664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12817
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