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An inhibitor of soluble epoxide hydrolase ameliorates diabetes-induced learning and memory impairment in rats

BACKGROUND: Pharmacological inhibition of soluble epoxide hydrolase (sEH) enhances the synaptic function in the CNS and has a protective role in cognitive decline. We hypothesized that the sEH inhibitor TPPU might prevent the diabetes-induced decline in learning and memory which is associated with a...

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Detalhes bibliográficos
Publicado no:Prostaglandins Other Lipid Mediat
Main Authors: Minaz, Nathani, Razdan, Rema, Hammock, Bruce D., Goswami, Sumanta Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402559/
https://ncbi.nlm.nih.gov/pubmed/29751149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2018.05.004
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