Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion induced cardiac damage in normal, hypertensive and diabetic rats

AIM: We designed a study to evaluate the cardioprotective effect of two soluble epoxide hydrolase (sEH) inhibitors, 1-(1-propanoylpiperidin-4-yl)-3-(4-trifluoromethoxy)phenyl)urea (TPPU) and trans-4-{4-[3-(4-trifluoromethoxyphenyl)-ureido]cyclohexyloxy}benzoic acid (t-TUCB), in ischemia-reperfusion...

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Detalhes bibliográficos
Publicado no:Cardiovasc Ther
Main Authors: Islam, Oliul, Patil, Prashanth, Goswami, Sumanta K., Razdan, Rema, Inamdar, Mohammed N., Rizwan, Mohammed, Mathew, Jubin, Inceoglu, Bora, Stephen Lee, Kin S., Hwang, Sung H., Hammock, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597338/
https://ncbi.nlm.nih.gov/pubmed/28296232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1755-5922.12259
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