Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors

[Image: see text] Fatty acid amide hydrolase (FAAH) is responsible for regulating concentrations of the endocannabinoid arachidonoyl ethanolamide. Multiple FAAH inhibitors have been developed for clinical trials and have failed to demonstrate efficacy at treating pain, despite promising preclinical...

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Bibliografske podrobnosti
izdano v:ACS Omega
Main Authors: Kodani, Sean D., Wan, Debin, Wagner, Karen M., Hwang, Sung Hee, Morisseau, Christophe, Hammock, Bruce D.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2018
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6210075/
https://ncbi.nlm.nih.gov/pubmed/30411058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01625
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