Design and Potency of Dual Soluble Epoxide Hydrolase/Fatty Acid Amide Hydrolase Inhibitors

[Image: see text] Fatty acid amide hydrolase (FAAH) is responsible for regulating concentrations of the endocannabinoid arachidonoyl ethanolamide. Multiple FAAH inhibitors have been developed for clinical trials and have failed to demonstrate efficacy at treating pain, despite promising preclinical...

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Bibliographic Details
Published in:ACS Omega
Main Authors: Kodani, Sean D., Wan, Debin, Wagner, Karen M., Hwang, Sung Hee, Morisseau, Christophe, Hammock, Bruce D.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2018
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6210075/
https://ncbi.nlm.nih.gov/pubmed/30411058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01625
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