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LINGO‐1 antibody ameliorates myelin impairment and spatial memory deficits in the early stage of 5XFAD mice

AIMS: Multiple evidence has indicated that myelin injury is common in Alzheimer's disease (AD). However, whether myelin injury is an early event in AD and the relationship between it and cognitive function is still elusive. METHODS: Spatial memory of 5XFAD mice was determined by Morris water ma...

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Vydáno v:CNS Neurosci Ther
Hlavní autoři: Wu, Di, Tang, Xiang, Gu, Li‐Hua, Li, Xiao‐Li, Qi, Xin‐Yang, Bai, Feng, Chen, Xiao‐Chun, Wang, Jian‐Zhi, Ren, Qing‐Guo, Zhang, Zhi‐Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489849/
https://ncbi.nlm.nih.gov/pubmed/29427384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12809
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