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LINGO-1 antibody ameliorates myelin impairment and spatial memory deficits in experimental autoimmune encephalomyelitis mice

More than 50% of multiple sclerosis patients develop cognitive impairment. However, the underlying mechanisms are still unclear, and there is no effective treatment. LINGO-1 (LRR and Ig domain containing NOGO receptor interacting protein 1) has been identified as an inhibitor of oligodendrocyte diff...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sun, Jun-Jun, Ren, Qing-Guo, Xu, Lin, Zhang, Zhi-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585639/
https://ncbi.nlm.nih.gov/pubmed/26383267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14235
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