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LINGO‐1 antibody ameliorates myelin impairment and spatial memory deficits in the early stage of 5XFAD mice

AIMS: Multiple evidence has indicated that myelin injury is common in Alzheimer's disease (AD). However, whether myelin injury is an early event in AD and the relationship between it and cognitive function is still elusive. METHODS: Spatial memory of 5XFAD mice was determined by Morris water ma...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Wu, Di, Tang, Xiang, Gu, Li‐Hua, Li, Xiao‐Li, Qi, Xin‐Yang, Bai, Feng, Chen, Xiao‐Chun, Wang, Jian‐Zhi, Ren, Qing‐Guo, Zhang, Zhi‐Jun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489849/
https://ncbi.nlm.nih.gov/pubmed/29427384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12809
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