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LINGO‐1 antibody ameliorates myelin impairment and spatial memory deficits in the early stage of 5XFAD mice

AIMS: Multiple evidence has indicated that myelin injury is common in Alzheimer's disease (AD). However, whether myelin injury is an early event in AD and the relationship between it and cognitive function is still elusive. METHODS: Spatial memory of 5XFAD mice was determined by Morris water ma...

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Dades bibliogràfiques
Publicat a:CNS Neurosci Ther
Autors principals: Wu, Di, Tang, Xiang, Gu, Li‐Hua, Li, Xiao‐Li, Qi, Xin‐Yang, Bai, Feng, Chen, Xiao‐Chun, Wang, Jian‐Zhi, Ren, Qing‐Guo, Zhang, Zhi‐Jun
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489849/
https://ncbi.nlm.nih.gov/pubmed/29427384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12809
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