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Substituent Effects on the Coordination Chemistry of Metal-Binding Pharmacophores

The combination of XAS, UV-vis, NMR and EPR was used to examine the binding of a series of α-hydroxythiones to CoCA. All three appear to bind preferentially in their neutral, protonated forms. Two of the three clearly bind in a monodentate fashion, through the thione sulfur alone. Thiomaltol (TM) ap...

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Detalhes bibliográficos
Publicado no:Inorg Chem
Main Authors: Craig, Whitney R., Baker, Tessa W., Marts, Amy R., DeGenova, Daniel T., Martin, David P., Reed, Garrett C., McCarrick, Robert M., Crowder, Michael W., Cohen, Seth M., Tierney, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6489498/
https://ncbi.nlm.nih.gov/pubmed/28898098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.inorgchem.7b01661
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