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‘Unconventional’ Coordination Chemistry by Metal Chelating Fragments in a Metalloprotein Active Site

[Image: see text] The binding of three closely related chelators: 5-hydroxy-2-methyl-4H-pyran-4-thione (allothiomaltol, ATM), 3-hydroxy-2-methyl-4H-pyran-4-thione (thiomaltol, TM), and 3-hydroxy-4H-pyran-4-thione (thiopyromeconic acid, TPMA) to the active site of human carbonic anhydrase II (hCAII)...

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Detalhes bibliográficos
Main Authors: Martin, David P., Blachly, Patrick G., Marts, Amy R., Woodruff, Tessa M., de Oliveira, César A. F., McCammon, J. Andrew, Tierney, David L., Cohen, Seth M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104174/
https://ncbi.nlm.nih.gov/pubmed/24635441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500616m
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