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Effect of Donor Atom Identity on Metal Binding Pharmacophore Coordination
The inhibition and binding of three metal-binding pharmacophores (MBPs), 2-hydroxycyclohepta-2,4,6-trien-1-one (tropolone), 2-mercaptopyridine-N-oxide (1,2-HOPTO), and 2-hydroxycyclohepta-2,4,6-triene-1-thione (thiotropolone) to human carbonic anhydrase II (hCAII) and a mutant protein hCAII L198G we...
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| Publicado no: | J Biol Inorg Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5493394/ https://ncbi.nlm.nih.gov/pubmed/28389830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-017-1454-3 |
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