In vitro study of the Polo‐like kinase 1 inhibitor volasertib in non‐small‐cell lung cancer reveals a role for the tumor suppressor p53

Polo‐like kinase 1 (Plk1), a master regulator of mitosis and the DNA damage response, is considered to be an intriguing target in the research field of mitotic intervention. The observation that Plk1 is overexpressed in multiple human malignancies, including non‐small‐cell lung cancer (NSCLC), gave...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Oncol
Egile Nagusiak: Van den Bossche, Jolien, Deben, Christophe, De Pauw, Ines, Lambrechts, Hilde, Hermans, Christophe, Deschoolmeester, Vanessa, Jacobs, Julie, Specenier, Pol, Pauwels, Patrick, Vermorken, Jan Baptist, Peeters, Marc, Lardon, Filip, Wouters, An
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487694/
https://ncbi.nlm.nih.gov/pubmed/30859681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12477
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