Mitochondrial membrane potential played crucial roles in the accumulation of berberine in HepG2 cells

Berberine is a natural alkaloid that has antineoplastic effects. However, in hepatoma cells like HepG2, the expressions of uptake transporters are minimal but efflux transporters are relatively high. Hence, how berberine enters and reaches a cytocidal concentration remains to be elucidated. In the p...

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Vydáno v:Biosci Rep
Hlavní autoři: Li, Qiao, Zhou, Ting, Liu, Chang, Wang, Xiao-Yu, Zhang, Ji-Quan, Wu, Fei, Lin, Ge, Ma, Yue-Ming, Ma, Bing-Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487271/
https://ncbi.nlm.nih.gov/pubmed/30944202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190477
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