Mitochondrial membrane potential played crucial roles in the accumulation of berberine in HepG2 cells

Berberine is a natural alkaloid that has antineoplastic effects. However, in hepatoma cells like HepG2, the expressions of uptake transporters are minimal but efflux transporters are relatively high. Hence, how berberine enters and reaches a cytocidal concentration remains to be elucidated. In the p...

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Bibliographic Details
Published in:Biosci Rep
Main Authors: Li, Qiao, Zhou, Ting, Liu, Chang, Wang, Xiao-Yu, Zhang, Ji-Quan, Wu, Fei, Lin, Ge, Ma, Yue-Ming, Ma, Bing-Liang
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487271/
https://ncbi.nlm.nih.gov/pubmed/30944202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190477
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