Mitochondrial membrane potential played crucial roles in the accumulation of berberine in HepG2 cells

Berberine is a natural alkaloid that has antineoplastic effects. However, in hepatoma cells like HepG2, the expressions of uptake transporters are minimal but efflux transporters are relatively high. Hence, how berberine enters and reaches a cytocidal concentration remains to be elucidated. In the p...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Li, Qiao, Zhou, Ting, Liu, Chang, Wang, Xiao-Yu, Zhang, Ji-Quan, Wu, Fei, Lin, Ge, Ma, Yue-Ming, Ma, Bing-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487271/
https://ncbi.nlm.nih.gov/pubmed/30944202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190477
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