Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation

BACKGROUND: Hepatocellular carcinoma (HCC), the primary liver cancer, is one of the most malignant human tumors with extremely poor prognosis. The aim of this study was to investigate the anti-cancer effect of berberine in a human hepatocellular carcinoma cell line (HepG2), and to study the underlyi...

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Detalhes bibliográficos
Main Authors: Yu, Rong, Zhang, Zhi-qing, Wang, Bin, Jiang, Hong-xin, Cheng, Lei, Shen, Li-ming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079188/
https://ncbi.nlm.nih.gov/pubmed/24991192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-14-49
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