Mitochondrial membrane potential played crucial roles in the accumulation of berberine in HepG2 cells

Berberine is a natural alkaloid that has antineoplastic effects. However, in hepatoma cells like HepG2, the expressions of uptake transporters are minimal but efflux transporters are relatively high. Hence, how berberine enters and reaches a cytocidal concentration remains to be elucidated. In the p...

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Bibliografiske detaljer
Udgivet i:Biosci Rep
Main Authors: Li, Qiao, Zhou, Ting, Liu, Chang, Wang, Xiao-Yu, Zhang, Ji-Quan, Wu, Fei, Lin, Ge, Ma, Yue-Ming, Ma, Bing-Liang
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487271/
https://ncbi.nlm.nih.gov/pubmed/30944202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190477
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