Structural basis for auxiliary subunit KCTD16 regulation of the GABA(B) receptor

Metabotropic GABA(B) receptors mediate a significant fraction of inhibitory neurotransmission in the brain. Native GABA(B) receptor complexes contain the principal subunits GABA(B1) and GABA(B2), which form an obligate heterodimer, and auxiliary subunits, known as potassium channel tetramerization d...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Zuo, Hao, Glaaser, Ian, Zhao, Yulin, Kurinov, Igor, Mosyak, Lidia, Wang, Haonan, Liu, Jonathan, Park, Jinseo, Frangaj, Aurel, Sturchler, Emmanuel, Zhou, Ming, McDonald, Patricia, Geng, Yong, Slesinger, Paul A., Fan, Qing R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486783/
https://ncbi.nlm.nih.gov/pubmed/30971491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1903024116
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