Altered emotionality and neuronal excitability in mice lacking KCTD12, an auxiliary subunit of GABA(B) receptors associated with mood disorders

Gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the brain, is fundamental to brain function and implicated in the pathophysiology of several neuropsychiatric disorders. GABA activates G-protein-coupled GABA(B) receptors comprising principal GABA(B1) and GABA(B2) subunits as...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Cathomas, F, Stegen, M, Sigrist, H, Schmid, L, Seifritz, E, Gassmann, M, Bettler, B, Pryce, C R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445757/
https://ncbi.nlm.nih.gov/pubmed/25689571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.8
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