MRE11 UFMylation promotes ATM activation

A proper DNA damage response (DDR) is essential to maintain genome integrity and prevent tumorigenesis. DNA double-strand breaks (DSBs) are the most toxic DNA lesion and their repair is orchestrated by the ATM kinase. ATM is activated via the MRE11–RAD50–NBS1 (MRN) complex along with its autophospho...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Wang, Zhifeng, Gong, Yamin, Peng, Bin, Shi, Ruifeng, Fan, Dan, Zhao, Hongchang, Zhu, Min, Zhang, Haoxing, Lou, Zhenkun, Zhou, Jianwei, Zhu, Wei-Guo, Cong, Yu-Sheng, Xu, Xingzhi
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486557/
https://ncbi.nlm.nih.gov/pubmed/30783677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz110
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars