Mre11 modulates the fidelity of fusion between short telomeres in human cells

The loss of telomere function can result in the fusion of telomeres with other telomeric loci, or non-telomeric double-stranded DNA breaks. Sequence analysis of fusion events between short dysfunctional telomeres in human cells has revealed that fusion is characterized by a distinct molecular signat...

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Detalhes bibliográficos
Main Authors: Tankimanova, Maira, Capper, Rebecca, Letsolo, Boitelo T., Rowson, Jan, Jones, Rhiannon E., Britt-Compton, Bethan, Taylor, A. Malcolm R., Baird, Duncan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315324/
https://ncbi.nlm.nih.gov/pubmed/22139912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1117
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