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DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase
Fusion of critically short or damaged telomeres is associated with the genomic rearrangements that support malignant transformation. We have demonstrated the fundamental contribution of DNA ligase 4-dependent classical non-homologous end-joining to long-range inter-chromosomal telomere fusions. In c...
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| Gepubliceerd in: | Nucleic Acids Res |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6411840/ https://ncbi.nlm.nih.gov/pubmed/30590694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1279 |
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