A carregar...
Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair
The Mre11 complex (Mre11-Rad50-Nbs1 or MRN) binds double-strand breaks where it interacts with CtIP/Ctp1/Sae2 and ATM/Tel1 to preserve genome stability through its functions in homology-directed repair, checkpoint signaling and telomere maintenance. Here, we combine biochemical, structural and in vi...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526295/ https://ncbi.nlm.nih.gov/pubmed/23080121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks954 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|