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Dynamic Kinetochore Size Regulation Promotes Microtubule Capture and Chromosome Biorientation in Mitosis

Faithful chromosome segregation depends on the ability of sister kinetochores to attach to spindle microtubules. The outer layer of kinetochores transiently expands in early mitosis to form a fibrous corona, and compacts upon microtubule capture. Here we show that the dynein adaptor Spindly and the...

詳細記述

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書誌詳細
出版年:Nat Cell Biol
主要な著者: Sacristan, Carlos, Ahmad, Misbha Ud Din, Keller, Jenny, Fermie, Job, Groenewold, Vincent, Tromer, Eelco, Fish, Alexander, Melero, Roberto, Carazo, José María, Klumperman, Judith, Musacchio, Andrea, Perrakis, Anastassis, Kops, Geert JPL
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485389/
https://ncbi.nlm.nih.gov/pubmed/29915359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0130-3
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