A Novel Peptide Interfering with proBDNF-Sortilin Interaction Alleviates Chronic Inflammatory Pain

Rationale: Brain-derived neurotrophic factor (BDNF) is a key mediator in the development of chronic pain. Sortilin is known to interact with proBDNF and regulate its activity-dependent secretion in cortical neurons. In a rat model of inflammatory pain with intraplantar injection of complete Freund&#...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Ho, Idy H.T., Liu, Xiaodong, Zou, Yidan, Liu, Taian, Hu, Wei, Chan, Hung, Tian, Yuanyuan, Zhang, Yuchen, Li, Qing, Kou, Shanglong, Chan, Chee Sam, Gin, Tony, Cheng, Christopher H.K., Wong, Sunny H., Yu, Jun, Zhang, Lin, Wu, William K.K., Chan, Matthew T.V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2019
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485195/
https://ncbi.nlm.nih.gov/pubmed/31037129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.29703
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi