ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75(NTR) and Sortilin

Brain-derived neurotrophic factor (BDNF) is best characterized for critical roles in neuronal survival, differentiation, and synaptic modulation mediated by the TrkB receptor tyrosine kinase. Developmentally regulated death signaling by BDNF has also been demonstrated via activation of p75(NTR). Bec...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Teng, Henry K., Teng, Kenneth K., Lee, Ramee, Wright, Saundrene, Tevar, Seema, Almeida, Ramiro D., Kermani, Pouneh, Torkin, Risa, Chen, Zhe-Yu, Lee, Francis S., Kraemer, Rosemary T., Nykjaer, Anders, Hempstead, Barbara L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724992/
https://ncbi.nlm.nih.gov/pubmed/15930396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5123-04.2005
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