ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75(NTR) and Sortilin

Brain-derived neurotrophic factor (BDNF) is best characterized for critical roles in neuronal survival, differentiation, and synaptic modulation mediated by the TrkB receptor tyrosine kinase. Developmentally regulated death signaling by BDNF has also been demonstrated via activation of p75(NTR). Bec...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: Teng, Henry K., Teng, Kenneth K., Lee, Ramee, Wright, Saundrene, Tevar, Seema, Almeida, Ramiro D., Kermani, Pouneh, Torkin, Risa, Chen, Zhe-Yu, Lee, Francis S., Kraemer, Rosemary T., Nykjaer, Anders, Hempstead, Barbara L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2005
Soggetti:
Cellular/Molecular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724992/
https://ncbi.nlm.nih.gov/pubmed/15930396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5123-04.2005
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi