ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75(NTR) and Sortilin

Brain-derived neurotrophic factor (BDNF) is best characterized for critical roles in neuronal survival, differentiation, and synaptic modulation mediated by the TrkB receptor tyrosine kinase. Developmentally regulated death signaling by BDNF has also been demonstrated via activation of p75(NTR). Bec...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Teng, Henry K., Teng, Kenneth K., Lee, Ramee, Wright, Saundrene, Tevar, Seema, Almeida, Ramiro D., Kermani, Pouneh, Torkin, Risa, Chen, Zhe-Yu, Lee, Francis S., Kraemer, Rosemary T., Nykjaer, Anders, Hempstead, Barbara L.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2005
Teme:
Cellular/Molecular
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724992/
https://ncbi.nlm.nih.gov/pubmed/15930396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5123-04.2005
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