Effect of Doxepin Mouthwash or Diphenhydramine-Lidocaine-Antacid Mouthwash vs Placebo on Radiotherapy-Related Oral Mucositis Pain: The Alliance A221304 Randomized Clinical Trial

IMPORTANCE: Oral mucositis causes substantial morbidity during head and neck radiotherapy. In a randomized study, doxepin mouthwash was shown to reduce oral mucositis–related pain. A common mouthwash comprising diphenhydramine-lidocaine-antacid is also widely used. OBJECTIVE: To evaluate the effect...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JAMA
Egile Nagusiak: Sio, Terence T., Le-Rademacher, Jennifer G., Leenstra, James L., Loprinzi, Charles L., Rine, Grant, Curtis, Amarinthia, Singh, Anurag K., Martenson, James A., Novotny, Paul J., Tan, Angelina D., Qin, Rui, Ko, Stephen J., Reiter, Paul L., Miller, Robert C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Medical Association 2019
Gaiak:
Original Investigation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484809/
https://ncbi.nlm.nih.gov/pubmed/30990550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.3504
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