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Brain histamine H(1) receptor occupancy of orally administered antihistamines, bepotastine and diphenhydramine, measured by PET with (11)C-doxepin

AIMS: Antihistamines are frequently used for treating various allergic diseases, but often induce sedation. The degree of sedation can be evaluated by measuring histamine H(1) receptor occupancy (H(1)RO) in the brain using positron emission tomography (PET). The aim was to measure H(1)RO of bepotast...

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Detalhes bibliográficos
Main Authors: Tashiro, Manabu, Duan, Xudong, Kato, Motohisa, Miyake, Masayasu, Watanuki, Shoichi, Ishikawa, Yoichi, Funaki, Yoshihito, Iwata, Ren, Itoh, Masatoshi, Yanai, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2485223/
https://ncbi.nlm.nih.gov/pubmed/18410464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03143.x
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