Brain histamine H(1) receptor occupancy of orally administered antihistamines, bepotastine and diphenhydramine, measured by PET with (11)C-doxepin

AIMS: Antihistamines are frequently used for treating various allergic diseases, but often induce sedation. The degree of sedation can be evaluated by measuring histamine H(1) receptor occupancy (H(1)RO) in the brain using positron emission tomography (PET). The aim was to measure H(1)RO of bepotast...

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Bibliografski detalji
Glavni autori: Tashiro, Manabu, Duan, Xudong, Kato, Motohisa, Miyake, Masayasu, Watanuki, Shoichi, Ishikawa, Yoichi, Funaki, Yoshihito, Iwata, Ren, Itoh, Masatoshi, Yanai, Kazuhiko
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2008
Teme:
Pharmacodynamics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2485223/
https://ncbi.nlm.nih.gov/pubmed/18410464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03143.x
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