The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions

Conditional knockout (KO) mouse models are invaluable for elucidating the physiological roles of platelets. The Platelet factor 4-Cre recombinase (Pf4-Cre) transgenic mouse is the current model of choice for generating megakaryocyte/platelet-specific KO mice. Platelets and leukocytes work closely to...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Nagy, Zoltan, Vögtle, Timo, Geer, Mitchell J., Mori, Jun, Heising, Silke, Di Nunzio, Giada, Gareus, Ralph, Tarakhovsky, Alexander, Weiss, Arthur, Neel, Benjamin G., Desanti, Guillaume E., Mazharian, Alexandra, Senis, Yotis A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2019
Soggetti:
Platelets and Thrombopoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484457/
https://ncbi.nlm.nih.gov/pubmed/30429161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-09-877787
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