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QueE: A radical SAM enzyme involved in the biosynthesis of 7-deazapurine containing natural products
7-Carboxy-7-deazaguanine (CDG) is a common intermediate in the biosynthesis of 7-deazapurine-contianing natural products. The biosynthesis of CDG from GTP requires three enzymes: GTP cyclohydrolase I, 6-carboxy-5,6,7,8-tetrahydropterin (CPH(4)) synthase, and CDG synthase (QueE). QueE is a member of...
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| Udgivet i: | Methods Enzymol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6484087/ https://ncbi.nlm.nih.gov/pubmed/30097106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.05.001 |
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