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TYW1: A radical SAM enzyme involved in the biosynthesis of wybutosine bases
Transfer RNA is extensively modified by the actions of a variety of enzymes. The radical S-adenosyl-l-methionine enzyme TYW1 modifies tRNA(Phe) forming the characteristic tricyclic ring via the condensation of carbons 2 and 3 of pyruvate. This chapter details methods that are required for studies of...
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| Publicado no: | Methods Enzymol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6448148/ https://ncbi.nlm.nih.gov/pubmed/30097090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.04.024 |
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