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Radical mediated ring formation in the biosynthesis of the hypermodified tRNA base wybutosine
Wyosine and its derivatives are highly modified, acid labile tricyclic bases found at position 37 of tRNA(Phe) in archaea and eukarya. The formation of the common 4-demethylwyosine structural feature entails condensation of pyruvate and N-methylguanosine catalyzed by TYW1. This review will focus on...
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| Publicado no: | Curr Opin Chem Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4320972/ https://ncbi.nlm.nih.gov/pubmed/23856057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2013.05.035 |
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