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Targeting insulin to the liver corrects defects in glucose metabolism caused by peripheral insulin delivery

Peripheral hyperinsulinemia resulting from subcutaneous insulin injection is associated with metabolic defects that include abnormal glucose metabolism. The first aim of this study was to quantify the impairments in liver and muscle glucose metabolism that occur when insulin is delivered via a perip...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Edgerton, Dale S., Scott, Melanie, Farmer, Ben, Williams, Phillip E., Madsen, Peter, Kjeldsen, Thomas, Brand, Christian L., Fledelius, Christian, Nishimura, Erica, Cherrington, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6483654/
https://ncbi.nlm.nih.gov/pubmed/30830873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126974
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