Insulin’s direct hepatic effect explains the inhibition of glucose production caused by insulin secretion

Insulin can inhibit hepatic glucose production (HGP) by acting directly on the liver as well as indirectly through effects on adipose tissue, pancreas, and brain. While insulin’s indirect effects are indisputable, their physiologic role in the suppression of HGP seen in response to increased insulin...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Edgerton, Dale S., Kraft, Guillaume, Smith, Marta, Farmer, Ben, Williams, Phillip E., Coate, Katie C., Printz, Richard L., O’Brien, Richard M., Cherrington, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358484/
https://ncbi.nlm.nih.gov/pubmed/28352665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91863
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