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Importance of the route of insulin delivery to its control of glucose metabolism
Pancreatic insulin secretion produces an insulin gradient at the liver compared with the rest of the body (approximately 3:1). This physiological distribution is lost when insulin is injected subcutaneously, causing impaired regulation of hepatic glucose production and whole body glucose uptake, as...
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| Publicado no: | Am J Physiol Endocrinol Metab |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8238128/ https://ncbi.nlm.nih.gov/pubmed/33813879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00628.2020 |
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