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Importance of the route of insulin delivery to its control of glucose metabolism

Pancreatic insulin secretion produces an insulin gradient at the liver compared with the rest of the body (approximately 3:1). This physiological distribution is lost when insulin is injected subcutaneously, causing impaired regulation of hepatic glucose production and whole body glucose uptake, as...

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Podrobná bibliografie
Vydáno v:Am J Physiol Endocrinol Metab
Hlavní autoři: Edgerton, Dale S., Moore, Mary C., Gregory, Justin M., Kraft, Guillaume, Cherrington, Alan D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238128/
https://ncbi.nlm.nih.gov/pubmed/33813879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00628.2020
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