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Importance of the route of insulin delivery to its control of glucose metabolism

Pancreatic insulin secretion produces an insulin gradient at the liver compared with the rest of the body (approximately 3:1). This physiological distribution is lost when insulin is injected subcutaneously, causing impaired regulation of hepatic glucose production and whole body glucose uptake, as...

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Dades bibliogràfiques
Publicat a:Am J Physiol Endocrinol Metab
Autors principals: Edgerton, Dale S., Moore, Mary C., Gregory, Justin M., Kraft, Guillaume, Cherrington, Alan D.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238128/
https://ncbi.nlm.nih.gov/pubmed/33813879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00628.2020
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