Insulin’s direct hepatic effect explains the inhibition of glucose production caused by insulin secretion

Insulin can inhibit hepatic glucose production (HGP) by acting directly on the liver as well as indirectly through effects on adipose tissue, pancreas, and brain. While insulin’s indirect effects are indisputable, their physiologic role in the suppression of HGP seen in response to increased insulin...

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Publicado en:JCI Insight
Autores principales: Edgerton, Dale S., Kraft, Guillaume, Smith, Marta, Farmer, Ben, Williams, Phillip E., Coate, Katie C., Printz, Richard L., O’Brien, Richard M., Cherrington, Alan D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358484/
https://ncbi.nlm.nih.gov/pubmed/28352665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91863
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